Cognition™ was designed for those whose career and creativity depend on their ability to focus, concentrate, stay centered and think clearer. Known as a nootropic, it is a highly concentrated liquid brain-boosting supplement, a mix of Ayurvedic plants and compounds that each have been shown to support beneficial effects on brain health and function.
Cognition™ is the right tool for those who need sections of time when the mind is firing on all cylinders; when there is a boost in creativity, mood uplift, clarity, being centered, clear decision making, amplified determination, and the overall ability to get things done. This includes:
I started creating and marketing plant-based brain tonics back in 2006. Now with the new Cognition™ formula, we have the best plant-based nootropic in the world today.
No sugar. No caffeine. No stimulants. No artificial ingredients or preservatives. Just plants and compounds that give the brain what it needs to work well.
With Cognition™, the driving force was to create the the best brain-enhancing formula—commonly called a nootropic—in the world, both in strength and efficacy. This required three elements:
Every cognitive-enhancing organic compound in the world is bitter—100% of them. Trying to avoid this alkaloidal fact is what leads developers to creating weak products by drying and encapsulation, or dramatically lowering the ingredient totals in order to taste better.
But an effective nootropic is not candy. It’s not a gummy bear, it’s not even a fun beverage. It’s an intense tonic designed to work. If the goal is better thinking and focus, and being the absolute best in the world, then you can not avoid bitter. So we didn’t—we embraced it.
Fortunately the solution is easy. While some customers place Cognition™ directly under the tongue and enjoy the bitter orange taste, it’s also easy to diffuse each serving in a bit of juice, water, tea, oat milk, or other dilution mediums. Hot or cold, it does not impact its efficacy.
We started with efficacious amounts of each ingredient—the amount that actually produces the result—and then worked backwards. This made the formula relatively expensive, and it also made it quite… stuffed. There is so much active ingredient in 4-ounce bottle that our chemists had a hard time getting it all in.
This third part to Cognition’s strength is an innovative technology called Supercritical Fluid Extraction, or SCFE. SCFE uses extremely cold CO2 to separate the terpenes, alkaloids, bitters and other active ingredients from Ayurvedic plants to end up with strengths far beyond the methods available to us even back in 2013. Instead of 1-to-1 raw dried herb capsules, or classic steam and alcohol tinctures in the 5:1 range, SCFE allows us to get beyond even 70:1 concentrations.
The resulting resinous matrix is expensive—one of Cognition’s ingredient cost us $900 per kilo—but once you try it, you will realize why. It has allowed us to take natural plant-based nootropics to a whole new level.
Drone photo of one of the four farms where Synaptic’s plants are grown, outside of Pune, India. No pesticides are used.
The harvested plants are then taken to this Supercritical Fluid Extraction manufacturing lab, where each plant is processed down to the concentrations shown in the above Supplement Facts panel.
A driving force behind Synaptic is to show people the power of plant-based formulas for their physical and mental well-being. This puts a paramount importance on knowing exactly where each ingredient comes from.
We spent months searching for the growers and manufacturers who know their farmers and had the documentation of how each plant is grown, and then had the technology to turn these plants into high concentrations.
This is the view up the hill from the farm. All plants are grown without pesticides or herbicides, and this requires being away from pollution sources and more in nature.
The valley farm where our Ayurvedic plants come from.
Extracts from the Bacopa monnieri leaf has been used for more than 1400 years by Ayurvedic practitioners for its support with memory and cognition. Recent 2020 research has focused primarily on Bacopa’s support of cognitive function, memory, learning, and concentration.
Our FDA-audited manufacturing lab takes 55 pounds of Bacopa monnieri leaf, and processes it through CO2 Supercritical Fluid Extraction, extracting the active and beneficial compounds to end up with just 1 pound of Bacopa concentrate.
It has been shown that Bacopa monnieri helps support healthy dendritic lengthening and branching. Dendrites are parts of nerve cells in the brain that are closely linked to learning and memory.
It also has many compounds that promotes and then supports healthy nerve cells in the brain for transmission for focus, concentration, learning and memory.
Bacopa monnieri also helps reduce stress and occasional anxiety by elevating your mood and promoting a healthy level of cortisol, a hormone that is closely linked to the stress level.
Also known as Intellect Tree in Sanskrit, the seed of Celastrus supports memory improvement by increasing acetylcholine levels in the brain. Its effect has been compared to piracetam, one of the earliest lab-produced nootropics. Supports memory, mood, and stress response. Our 4x extract is made into “black oil” which contains the most concentrated active compounds.
Centella asiatica has a particularly large amount of bioactive terpenes and other compounds, and has long been used as a mental rejuvenator for fatigue and concentration. Several mechanisms of actions have demonstrated support for protection against brain plaque (beta-amyloid) formation, and anti-stress and mood uplifting properties in pre-clinical studies.
These active compounds in Centella asiatica help to reduce stress, occasional anxiety, and mood swings by promoting levels of the healthy feel-good neurotransmitters called serotonin, dopamine, and norepinephrine.
AGP Choline (aka Alpha-GPC) is arguably the most clinically studied of all nootropics. Available only as a prescription until the late ’90s, AGP increases the amount of acetylcholine, and plays a supportive role in attention, concentration, memory formation and recall. It is naturally found in breast milk, meats and small fish, and Synaptic uses a vegan form derived from non-GMO soy.
By weight, A-glyceryl Phosphoryl Choline is the most efficient form of choline nootropic on the market. It’s also the most expensive. We use 333mg of 99% pure AGP choline in every 2ml serving.
Long used as a traditional nerve tonic for neuroprotection and inflammation, the US Department of Agriculture recently noted Convolvulus pluricaulis’ history as a medicinal plant that supports intellect and memory. Clinical studies further show that this plant induces a state of calm and peace, and this is why we use a 65x strength of this herb in Cognition.
Griffonia simplicifolia is the only plant in our Cognition formula not from India (it grows exclusively in Africa), and its seeds are the source of one of the most extraordinary nootropics that exists—the amino acid 5-Hydroxytryptophan, better known as 5-HTP, an important building block for the neurotransmitter serotonin. Most people familiar with 5-HTP use it to regulate the sleep cycle and appetite. But it’s biggest effect that we’ve seen is in supporting elevation of mood and well being.
The seeds of this legume contain the precursors to some of our brain’s most important neurotransmitters, including noradrenaline, dopamine, and serotonin. Ayurvedic medicine has used Mucuna pruriens extract for centuries for its neuroprotective properties.
Considered a preeminent plant in Ayurvedic medicine, the leaves of Ocimum sanctum studies show pharmacological actions including positive effects on memory, anti-depression, and boosting acetylcholine levels. We boost this further by concentrating this extract 33 times.
It’s too early to tell how big an impact our ground-breaking first product Cognition™ can cause. All the ingredients for change (quite literally) are there for that to happen. But there’s a good way to find out: get involved. Try it. Spread the word to those who need this.
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